Business Models
Research Overview
R & D Alliances
Developing deep scientific partnerships with global research institutions, establishing proprietary pipelines for drug product discovery and clinical assets.
Integrated Manufacturing Facility
In-licensing Technologies
- Process Optimization
- Development & Manufacturing
- Analytical Development
- Formulation Development
- Pre & Clinical Studies
Partner Programs In Development
Co-commercialization
Shared asset distribution, joint regulatory filings, and collaborative access to local and international commercial logistics to launch high-quality therapeutics fast.
We Make It Work – For Every Molecule
Successful development relies on a deep understanding of a molecule's unique characteristics. At avand, we have the knowledge and expertise to realize the true potential of your molecule, regardless of its complexity. By taking the right steps through our broad portfolio and platform processes, we help advance your molecule to IND and beyond.
Rise above complexity with our extensive portfolio & platforms
Our proprietary platforms make complexity simple for you. With our dedicated expertise, we help steer your development while minimizing risks and timelines.
Monoclonal Antibody variable to individual cases
Recombinants variable to individual cases
Diagnostic kits variable to individual cases
Nutraceuticals variable to individual cases
Therapeutic Protein variable to individual cases
One Plant, One-stop Process
- From development to clinical and commercial, we work with commercialization in mind.
- By applying experimental design to both upstream and downstream processes, we are able to achieve optimal yield, quality, and stability for a reliable clinical supply.
- Partner with Avand and take your molecule to IND and beyond.
- Our seamless one-stop solution delivers ultimate client satisfaction, allowing you to save cost and time.
- From cell line development to drug substance and drug product manufacturing, up to product lot release, our plant handles your product's entire production life cycle within a single site.
A Seamless End-to-end Solution
Consistently improving speed to market is a key strategic measure for Avand. We offer a completely integrated service at a single site – a seamless solution that paves the way for your discovery from early development through clinical and commercial manufacturing. This full-service offering enables our clients to bring their transformational biologics to market with utmost speed and cost-effectiveness without the hassle of multiple contracts and vendor management.
Early-Stage Development
Taking the right steps early, our streamlined platform and comprehensive portfolio enable a seamless path from gene discovery to IND submission.
Our Service Offerings:
- Cell Line Development.
- MCB Banking and Characterization.
- Upstream Process Development.
- Downstream Process Development.
- Formulation Development.
- Analytical Method Development.
- Non-GMP DS & DP Production & Stability Study.
- CMC Preparation & IND Filing Support.
Clinical Manufacturing
Reliability & Experience with a strong track record, our team can help you navigate complex regulatory processes with confidence. We ensure reliable supply at each clinical development phase.
Our Service Offerings:
- cGMP DS & DP Manufacturing for Clinical Phase I, II, III
- Single Use Production
- cGMP DS & DP Stability Studies
- Process Characterization & Validation
- Analytical Method Validation
- Release Testing
- Regulatory Filing Support
Commercial Manufacturing
Delivering On Time, In Full. Our multi-scale, cGMP-compliant DS and DP manufacturing facilities offer maximum flexibility and economies of scale, enabling seamless transition from clinical development to commercial production.
Our Service Offerings:
- Gap Assessment
- Process Control Strategy / Scale-Down Model Study
- Analytical Tech Transfer
- Engineering Run
- Process Performance Qualifications
- Release Testing
- Stability Testing
- Regulatory Filing Support
Development – Streamlined Process With A Faster Timeline
With Avand, you’ll have a partner with the expertise and solutions to strike the right balance while quickly laying a solid foundation for future success
Process Development Platform
| Upstream Process | Description |
|---|---|
| Upstream Process | Quick media selection Application of pre-defined operating parameters. |
| Downstream Process | 3-step purification : Capture, MMX, CEX 5-step filter : Depth, Micro, Nano, UF/DF. |
| Formulation Process | Screening matrix for pH, buffer, and excipient optimization without development. |
| Analytical Method | Pre-defined set of methods for product characterization and release/stability testing. |
| Process Characterization | Scale-down model qualification. Establishment of process parameter ranges for process control. |
Manufacturing: Multi-scale Solutions Enabling Maximum Flexibility
At Avand, we operate fully integrated modular facilities at a single site with the latest technologies across multiple scales. It houses multi-scale DS suites with single-use production.
Bioanalytical Testing: Comprehensive, Precise In-house Analytical Testing
Our comprehensive analytical testing services are carried out fully in-house from a single central location. This translates to significant time and cost savings for our clients.
Our Testing Capabilities
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Aseptic Fill/Finish: High Throughput Filling with Quality Assurance
DP fill/finish is one of the most delicate and critical steps in biomanufacturing. At Avand, we offer our clients the most up-to-date, yet flexible fill/finish service that ensures product stability and patient safety.
